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Spina bifida (myelomeningocele) is a congenital malformation that occurs during the first month of pregnancy.  As a result, a portion of the fetal spinal cord fails to close properly and the child is born with a part of the spinal nerve roots protruding from the back, forming what is known as a neural tube defect (NTD).  This defective closure can occur anywhere along the spine, from the neck to the rump bone and tail bones, but is most often found in the loin area. Enclosure of the spina bifida is performed as soon as possible, preferably within 24 hours of birth.

Cause is unknown
What causes NTD is still unknown, but hereditary factors and folic acid deficiency have been discussed.